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Tuesday, April 28, 2020 | History

2 edition of Iododeoxyuridine incorporation in rat and human prostate. found in the catalog.

Iododeoxyuridine incorporation in rat and human prostate.

L. J. Donaldson

Iododeoxyuridine incorporation in rat and human prostate.

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  • 33 Currently reading

Published by University of Birmingham in Birmingham .
Written in English


Edition Notes

Thesis (M.Sc.)- Univ. of Birmingham, Dept. of Anatomy.

ID Numbers
Open LibraryOL21354364M

  Results obtained in this study clearly demonstrate that daidzein, coumestrol and zearalenone affect lipogenesis and lipolysis in isolated rat adipocytes. Daidzein restricted both basal and insulin-stimulated glucose conversion to lipids (Fig. 1).   News - Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in the most promising areas of biotechnology and regenerative medicine, biomedical research, clinical medicine and surgery, technology and engineering, law, integrative medicine, public health, and environmental studies.   Rat dorsolateral prostate in culture thus provides a useful model for the studies on the mechanisms of hormone regulation of the prostate. This content is only available as a PDF. Author notes * " Part of this work was presented in abstract form at the Second International Symposium on Hormonal Manipulation of Cancer: Peptides, Growth Factors Cited by:   The US National Toxicology Program (NTP) has released partial results of a large study it’s conducting in rats and mice to try to determine whether cell phone use causes cancer. Cell phones give off a low-energy type of radiation called radiofrequency (RF) radiation when they’re in use, and that has caused concern over whether or not cell phones can increase cancer : Stacy Simon.

Trinity J. Bivalacqua, M.D., Ph.D., is the R. Christian B. Evensen Professor of Urology and Oncology and Director of Urologic Oncology at the James Buchanan Brady Urologic Institute. He was born in New Orleans, Louisiana and graduated from Tulane University with undergraduate, graduate and medical degrees. He joined the faculty after.


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Iododeoxyuridine incorporation in rat and human prostate. by L. J. Donaldson Download PDF EPUB FB2

Donaldson LJ, Thomas GH. Uptake of (I) iododeoxyuridine in cultured rat Iododeoxyuridine incorporation in rat and human prostate. book human prostate: effects of insulin and testosterone.

J Endocrinol. Apr; 69 (1)– Fuller DJ, Donaldson LJ, Thomas GH. Ornithine decarboxylase activity and: [I]iododeoxyuridine incorporation in rat prostate. Biochem J. Sep; (3)–Cited by: DNA synthetic activity was monitored in rat and human prostate using [I] iododeoxyuridine ([I]UdR).

Fresh prostate tissue from 6-week-old rats showed higher incorporation of [I]UdR than that from or week-old rats. During culture for up to 6 days in the absence of hormones, the incorporation of [I]UdR fell to a low level for Cited by: 7. Cell kinetics was investigated using [I] iododeoxyuridine and vincristine.

Both approaches demonstrated a spontaneous surge in proliferative activity of BPH reaching a peak at about Day 4.

In contrast, proliferative activity in rat prostate tended to fall over the period of days of by: 4. Ornithine decarboxylase activity and: [I]iododeoxyuridine incorporation in rat prostate. Fuller DJ, Donaldson LJ, Thomas GH. Biochem J, (3), 01 Sep Cited by: 12 articles | PMID: | PMCID: PMC Free to readCited by: 4.

The relationship between ornithine decarboxylase activity and [I]iododexyuridine incorporation was studied in prostates from castrated rats (aged 5, 26 and 80 weeks) injected daily with testosterone Cited by:   Fuller DJ, Donaldson LJ, Thomas GH.

Ornithine decarboxylase activity and: [I]iododeoxyuridine incorporation in rat prostate. Biochem J. Sep; (3)– [PMC free article] Guha SK, Jänne J. Inhibition of ornithine decarboxylase in vivo in rat ovary.

Biochem Biophys Res Commun. Mar 7; 75 (1)– Iododeoxyuridine is a halogenated pyrimidine and non-hypoxic cell radiosensitizer currently being used in clinical trials.

The amount of radiosensitiz Cited by:   The application of spores of the bacterium Clostridium oncolyticum s. butyricum (M 55) results in an increased incorporation of Iododeoxyuridine in tumors (amelanotic melanoma Fortner III of the golden hamster and Brown-Pearce carcinoma of the rabbit).

This leads to an improved scintigraphic demonstration of the by: 6. Divergent patterns of incorporation of bromodeoxyuridine and iododeoxyuridine in human colorectal tumor cell lines Article (PDF Available) in Biochemical Pharmacology 42(1) July with. Androgenic control of acetate incorporation into phospholipids and triacylglycerols in rat ventral prostate Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, Vol.

78, No. 1 Plasma steroids in benign prostatic hypertrophy and carcinoma of the prostate. Androgen Interaction with the Polyamine System of the Rat Prostate Article in Andrologia 19(2) March with 7 Reads How we measure 'reads'.

THE extensive introduction under cell culture conditions of 5-bromodeoxyuridine and 5-iododeoxyuridine into the deoxyribonucleic acid of a cell strain derived from a human Cited by: Ornithine decarboxylase activity and.

iododeoxyuridine incorporation in rat prostate. Biochem J ; 16 Takyi EEK, Fuller DJM, Donald Thomas GH. Deoxyribonucleic acid and polyamine syn- thesis in rat ventral by: Ensembl ENSG ENSMUSG UniProt P Q68FF9 RefSeq (mRNA) NM_ NM_ NM_ NM_ RefSeq (protein) NP_ NP_ NP_ NP_ Location (UCSC) Chr 5: – Mb Chr – Mb PubMed search Wikidata View/Edit Human View/Edit Mouse 3-oxo-5α-steroid 4-dehydrogenase 1 is an Aliases: SRD5A1, S5AR 1, steroid 5 alpha-reductase 1.

The second edition of Comparative Anatomy and Histology is aimed at the new rodent investigator as well as medical and veterinary pathologists who need to expand their knowledge base into comparative anatomy and Iododeoxyuridine incorporation in rat and human prostate. book. It guides the reader through normal mouse and rat anatomy and histology using direct comparison to the human.

Idoxuridine is an iodinated analogue of deoxyuridine, with antiviral activity against herpes simplex virus (HSV) and potential radiosensitizing ocular administration, idoxuridine (IUdR) is converted to its mono- di- and triphosphate forms, is incorporated into DNA and disrupts viral replication.

International Conference on Chemical Modifiers of Cancer Treatment February • Clearwater, Florida. select article Iododeoxyuridine incorporation and radiosensitization in three human tumor cell lines. Results from a phase II trial of etanidazole and radiation therapy in locally advanced prostate cancer.

5-Iodo-2'-deoxyuridine (IdUrd), a thymidine (TdR) analogue, can be radiolabelled with iodine, an Auger radiation emitter, to provoke double-strand breaks once incorporated into DNA of cancer cells.

We have previously shown that co-incubation of [I]IdUrd with unlabelled IdUrd provided an additive cytotoxicity in two human glioblastoma cell lines. This observation was unexpectedly Cited by:   Lawrence TS, Davis MA, McKeever PE, Maybaum J, Stetson PL, Normolle DP, et al.

Fluorodeoxyuridine-mediated modulation of iododeoxyuridine incorporation and radiosensitization in human colon cancer cells in vitro and in vivo. Cancer Res ;– PubMed Google ScholarCited by: Ensembl ENSG ENSMUSG UniProt Q Q9ESD1 RefSeq (mRNA) NM_ NM_ RefSeq (protein) NP_ n/a Location (UCSC) Chr – Mb Chr 7: – Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Prostasin is a protein that in humans is encoded by the PRSS8 gene.

This gene encodes a Aliases: PRSS8, CAP1, PROSTASIN, protease, serine. The Use of Uterine Vascular Clamping in the Pregnant Rat to Modify the Embryotoxic Effects of Anticancer Drugs. Robert L. Brent, Booker T. Bolden and Arthur Weiss. Cancer Res October 1 28 (10) ; Articles.

Localized Incorporation of Iododeoxyuridine from Polycation-complexed Iododeoxycytidylic Acid into DNA of Several Murine and. Ensembl ENSG ENSMUSG UniProt O Q RefSeq (mRNA) NM_ NM_ NM_ RefSeq (protein) NP_ NP_ NP_ Location (UCSC) Chr 8: – Mb Chr 3: – Mb PubMed search Wikidata View/Edit Human View/Edit Mouse hydroxycholesterol 7-alpha-hydroxylase also known as oxysterol and Aliases: CYP7B1, CBAS3, CP7B, SPG5A, cytochrome.

2′-Fluoro[14 C]-methylβ-D-arabinofuranosyluracil (FMAU) is an analog of thymidine (TdR) that is resistant to catabolism, is incorporated into DNA, and has been labeled with 11 C for use with positron emission compared the uptake and metabolism of [14 C]FMAU with that of [3 H]TdR in fast- and slow-growing cell lines of a rat prostate by: similar or superior % IUdR–DNA incorporation in the human tumor xenografts using oral IPdR given once daily × 14 days co m- pared to the maximum tolerated dose of IUdR as a continuous.

Read 3 answers by scientists with 2 recommendations from their colleagues to the question asked by Nuno Dinis Alves on Jun 4,   Of the nine biological trace elements, zinc, copper and selenium are important in reproduction in males and females. Zinc content is high in the adult testis, and the prostate has a higher concentration of zinc than any other organ of the body.

Zinc deficiency first impairs angiotensin converting enzyme (ACE) activity, and this in turn leads to depletion of testosterone and inhibition of Cited by: What is the best way to induce prostate cancer or hyperplasia in rats and what is the best biomarker.

Am doing some investigations on prostate cancer in rats. Prostate Cancer. This dose was fold less than previously reported, and comparable to doses of irradiation used clinically in standard fractionated radiotherapy for brain tumors.

When 9L rat gliosarcoma cells were infected with -1/lacZ in vitro and exposed to 2 Gy of external beam irradiation, there was a threefold increase in β-galactosidase by:   The normal human prostate accumulates the highest levels of zinc (Zn) of any soft tissue in the body.

The pool of zinc available to the body is known to significantly decrease with age. It is suggested that dietary Zn supplementation protects against oxidative damage and reduces the risk of cancer. Zinc sulfate and zinc gluconate were the most frequently mentioned in per os administration in Cited by: 8.

ALOX15 (also termed arachidonate lipoxygenase, lipoxygenase-1, LO-1, LOX-1) is, like other lipoxygenases, a seminal enzyme in the metabolism of polyunsaturated fatty acids to a wide range of physiologically and pathologically important products.

Gene Function. Kelavkar and Badr () stated that the ALOX15 gene product is implicated in antiinflammation, membrane remodeling, and Aliases: ALOX15, LOX, LOX-1, 15LOX-1. Ensembl ENSG ENSMUSG UniProt P P RefSeq (mRNA) NM_ NM_ NM_ RefSeq (protein) NP_ NP_ NP_ Location (UCSC) Chr 2: – Mb Chr 2: – Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Rnd3 is a small (~21 kDa) signaling G protein (to be specific, a GTPase), Aliases: RND3, ARHE, Rho8, RhoE, memB, Rnd3.

The prostate size ratio (prostate weight/rat body weight) was then calculated. Neither testosterone nor pumpkin seed oil had any significant influence on the weight gain of the rats. Testosterone significantly increased prostate size ratio (P rats fed with pumpkin seed oil at mg/ g of Cited by: Books at Amazon.

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The MT-3 gene was not inducible by CdCl 2 or lipopolysaccharide in rat testis and prostate. In the mouse and the human, relative MT-3 mRNA levels were lower than those found in the rat when compared with those present in brain. Testicular MT-3 transcript levels remained quite constant during rat postnatal development in animals aged from 6 to Cited by:   On rats were sacrificed, and the prostates were removed, cleaned, and weighed.

The prostate size ratio (prostate weight/rat body weight) was then calculated. TP significantly influenced the body weight gain of the rats and their food and water consumption, while AP at both doses tested reduced significantly these by: This book is to cancer research what the journals of the Voyage of the Beagle were to evolution.

All young cancer researchers should read this book for insight and inspiration.” —Dr. THOMAS ROCKWELL MACKIE, emeritus professor of medical physics, human oncology, and engineering physics, University of Wisconsin-Madison “This is an amazing by: 1.

Together with Janet F. Worthington, he authored the best-selling books for lay people The Prostate: A Guide for Men and the Women Who Love Them, which is published by Johns Hopkins University Press () and Warner Books () and more recently, Dr.

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Evaluation of the Testes. 2 Figure Legend: Figure 1 Testis, rete testis - normal. The rete testis is located at the hilus of File Size: KB. Issues in Sexuality and Sexual Behavior Research: Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Sexuality and Sexual Behavior Research.

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Rates of albumin and liver protein formation in control rats 5 to 7 weeks of age were and mg/lOO g of body weight per hour, respectively. The half-time of.

Rat is a common rodent of the order belongs to the class Mammalia of the subphylum Vertebrata and is often studied as a representative organism for mammals. As the structural organization of rats and humans are similar, it is widely used in medical research to evaluate the effects of medications, before releasing them for human use.

Diazepam-binding inhibitor (DBI)/acyl-CoA-binding protein (ACBP) is a highly conserved kD polypeptide expressed in various organs and implicated in the regulation of multiple biological processes such as GABA A /benzodiazepine receptor modulation, acyl-CoA metabolism, steroidogenesis, and insulin secretion.

To extend our knowledge about the biology of DBI/ACBP and Cited by: Cytogenetic damages from Iododeoxyuridine-induced radiosensitivity with and without Methoxyamine in human glioblastoma spheroids A NESHASTEHRIZ, M Saki, S KHOUEI CELL JOURNAL (YAKHTEH) 10 (),